Current Projects

“The study that the Kortney Rose Foundation is supporting will help speed the pace of brain tumor immunotherapy research at Children’s Hospital of Philadelphia. The study has developed CAR T-cells that show early efficacy in neuroblastoma mouse models, and they are seeing similar efficacy for high grade glioma cell lines.  We are immensely grateful for your generosity to help fast-track this important research to discover better treatments for children as quickly as possible.”

– Dr. Jessica Foster, M.D., attending physician in the Division of Oncology at Children’s Hospital of Philadelphia.

We are excited to be investing in a promising immunotherapy research project being led by Dr. Jessica Foster out of the Center for Data Driven Discovery in Biomedicine at CHOP and is part of the Open DIPG project. Dr. Foster has identified a common protein on the cells of several of the most deadly types of brain tumors. Using this protein as a target, researchers are working to develop new chimeric antigen receptor (CAR) T-cell immunotherapies that will save children’s lives.

“Just because a new medication works on cancer cells in a petri dish or mice doesn’t mean it will work in children or is safe in children. It is crucial to carefully and responsibly test new therapies…at present, we have over 30 open clinical trials for children with brain tumors. However, it is crucial to expand our clinical research program so that we can support the development and testing of new cutting edge therapies as well as expand the treatment options available for our patients today.”

– Dr. Michael J. Fisher, Chief of the Section of Neuro-Oncology, Children’s Hospital of Philadelphia

The Children’s Hospital of Philadelphia’s Neuro-Oncology Department sees more patients than any other children’s hospital in the country. The increase in patients that come through their unit has caused a need for growth in their program for clinician/researchers to adequately care for the patients as well as work on research to find better treatments and cures. The Kortney Rose Foundation is proud to be investing in this growth over the next couple of years.