I am sharing this exciting news I just received from CHOP!
A great reflection of what our funding has done to date.
We have some very exciting news to share. Today, the White House has released their Moonshot fact sheet with CHOP/CBTTC and CAVATICA receiving double-billing in the following two Moonshot statements. Attached you will also find the White House approved press release that will begin circulating today. We wanted you to be among the first to see these.
This is a validation of the work that Drs. Resnick, Storm, Waanders and the entire CBTTC team have been doing, and it is huge step forward in our efforts to encourage collaboration and open data sharing within pediatric cancer research. There is still much to be done, but none of these milestones would be possible without your support. THANK YOU!
- Today, the Children’s Brain Tumor Tissue Consortium, the Pacific Pediatric Neuro-Oncology Consortium, and Seven Bridges announce the release of CAVATICA, a data analysis platform designed to facilitate the rapid integration of data from multiple diseases affecting children, including cancer and other rare diseases like congenital disorders, epilepsy, and autism. Birth defects and neurological disorders have been linked to an increased incidence of cancer, however, uncovering these connections has been slowed because data generated to understand pediatric cancer cannot be easily compared to data generated for research into other rare diseases. CAVATICA will immediately make available more than 24 datasets for collaborative discovery spanning pediatric cancer to congenital heart defects, and these datasets will be interoperable with the Genomic Data Commons and other NIH data repositories to drive progress in our understanding and treatment of childhood cancer.
- Contribute & Change (C2) Cancer Commons – The nonprofit Open Commons Consortium and 12 acclaimed medical research centers and consortia are committed to improving the sharing of cancer genomic data by building a pilot biomedical data commons, the Contribute & Change (C2) Cancer Commons, and a pilot platform where multiple systems connect to share cancer data, the Cancer Commons Hub. The C2 Cancer Commons and the Cancer Commons Hub will more than double the molecular (e.g. genomics and proteomics data), medical imaging data, and clinical annotation data (e.g. clinical diagnosis, treatment, and patient history) currently available to researchers to fuel improvements in cancer outcomes. Over time, these systems will benefit cancer patients by providing the longitudinal data necessary to better determine which drugs and combination of drugs work best for specific tumors. The C2 Cancer Commons is based on the same open-source software that powers the NCI Genomic Data Commons (GDC), but will extend this capacity by hosting complementary datasets submitted by C2 members. As C2 Cancer Commons uses GDC data analysis processes to produce integrated and harmonized datasets for researchers, these new datasets will be shared in a similar fashion to publicly-funded projects such as NCI’s Cancer Genome Atlas.
At launch, Children’s Hospital of Philadelphia, Icahn School of Medicine at Mount Sinai, Indiana Clinical and Translational Sciences Institute (CTSI), Johns Hopkins University, NorthShore University HealthSystem, Northwell Health, and University of Chicago are participating in the Contribute & Change Cancer Commons Pilot. The C2 Cancer Commons, Molecular Evidence Development Consortium Biomedical Cancer Commons, American Association for Cancer Research Project GENIE (Genomics, Evidence, Neoplasia, Information, Exchange), Ontario Institute for Cancer Research’s Cancer Collaboratory, Cavatica Pediatric Cancer Cloud, and University of Chicago are participating in the Cancer Commons Hub. Additional medical research centers and cancer commons will be invited to participate in the consortium after the pilot phase.
Thank you to everyone who donated to support The Kortney Rose Foundation in our efforts to help the Children’s Brain Tumor Tissue Consortium (CBTTC) realize the launch of CAVATICA, pediatric data cancer cloud yesterday at the White House’s Cancer Moonshot event. Below are the key members of the CBTTC with Dr. Francis Collins (second from right) who is the Director of the National Institutes of Health (NIH). Congratulations to them for visualizing this dream and seeing it to fruition. We are proud to support their efforts and are confident it will change the landscape of pediatric cancer research.